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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Checkpoint Kinase (Chk)-Morusinol
Morusinol

Chemical Structure : Morusinol

CAS No.: 62949-93-3

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Morusinol

货号: PC-25459Not For Human Use, Lab Use Only.

Morusinol is a flavonoid isolated from Morus alba root bark, has antiplatelet activity and significantly inhibits arterial thrombosis in vivo,
induces cell cycle arrest and apoptosis via inhibition of DNA damage response in melanoma by CHK1 degradation through the ubiquitin-proteasome pathway.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Morusinol is a flavonoid isolated from Morus alba root bark, has antiplatelet activity and significantly inhibits arterial thrombosis in vivo,
induces cell cycle arrest and apoptosis via inhibition of DNA damage response in melanoma by CHK1 degradation through the ubiquitin-proteasome pathway.

物理化学性质&存储条件

分子量 438.48
分子式 C25H26O7
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(2,4-Dihydroxyphenyl)-5-hydroxy-3-(3-hydroxy-3-methylbutyl)-8,8-dimethyl-4H,8H-pyrano[2,3-f]chromen-4-one

参考文献

1. Lee JJ, et al. J Atheroscler Thromb. 2012;19(6):516-22.

2. Guo L, et al. Phytomedicine. 2023 Jun;114:154765.

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