Mocaciclib | CDK7 inhibitor | Probechem Biochemicals

Chemical Structure : Mocaciclib

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Mocaciclib (Q901)

货号: PC-24960Not For Human Use, Lab Use Only.

Mocaciclib (Q901) is a highly selective and potent CDK7 inhibitor, forms a covalent bond with C312 of the CDK7 C-terminal domain.

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生物&药学活性

Mocaciclib (Q901) is a highly selective and potent CDK7 inhibitor, forms a covalent bond with C312 of the CDK7 C-terminal domain.
Mocaciclib (Q901) demonstrates selective cytotoxic activities in a broad spectrum of solid tumor lineages.
Mocaciclib (Q901) is compound 64 extracted from Patent WO2019197546 A1.

物理化学性质&存储条件

分子量	609.71
分子式	C33H36FN9O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Fluoro-N-[1-[2-[[[2-[[[(3R,4R)-3-hydroxy-4-piperidinyl]methyl]amino]-8-(1-methylethyl)pyrazolo[1,5-a]-1,3,5-triazin-4-yl]amino]methyl]phenyl]-6-isoquinolinyl]-2-propenamide

参考文献

1. Patent WO2019197546 A1.

2. Donghoon Yu, et al. Cancer Res (2022) 82 (12_Supplement): 2574.

Mocaciclib (Q901)

生物&药学活性

物理化学性质&存储条件

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Mocaciclib (Q901)

生物&药学活性

物理化学性质&存储条件

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