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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Progesterone Receptor-Mifepristone
Mifepristone

Chemical Structure : Mifepristone

CAS No.: 84371-65-3

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Mifepristone (RU-486, RU486, RU38486)

货号: PC-22739Not For Human Use, Lab Use Only.

Mifepristone (RU-486, RU486) is a potent, selective progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50 of 0.2 nM and 2.6 nM respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Mifepristone (RU-486, RU486) is a potent, selective progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50 of 0.2 nM and 2.6 nM respectively.

物理化学性质&存储条件

分子量 429.60
分子式 C29H35NO2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Estra-4,9-dien-3-one, 11-[4-(dimethylamino)phenyl]-17-hydroxy-17-(1-propyn-1-yl)-, (11β,17β)-

参考文献

1. Jiang W, et al. Bioorg Med Chem. 2006 Oct 1;14(19):6726-32.

2. Juan Xu, et al. Steroids. 2020 Jul:159:108649.

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