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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Topoisomerase-Merbarone
Merbarone

Chemical Structure : Merbarone

CAS No.: 97534-21-9

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Merbarone (NSC 336628)

货号: PC-24928Not For Human Use, Lab Use Only.

Merbarone (NSC 336628) is a potent, orally active DNA topoisomerase II (Topo II) inhibitor, inhibits topoisomerase II-mediated DNA cleavage without stabilizing topo II-DNA covalent complexes.

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50 mg ￥1280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Merbarone (NSC 336628) is a potent, orally active DNA topoisomerase II (Topo II) inhibitor, inhibits topoisomerase II-mediated DNA cleavage without stabilizing topo II-DNA covalent complexes.

物理化学性质&存储条件

分子量 263.27
分子式 C11H9N3O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4,6-Dioxo-N-phenyl-2-thioxohexahydropyrimidine-5-carboxamide

参考文献

1. Cooney DA, et al. Biochem Pharmacol. 1985 Sep 15;34(18):3395-8.

2. Drake FH, et al. Cancer Res. 1989 May 15;49(10):2578-83.

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