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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-DNA Alkylator/Crosslinker-Melphalan
Melphalan

Chemical Structure : Melphalan

CAS No.: 148-82-3

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Melphalan (L-PAM)

货号: PC-45363Not For Human Use, Lab Use Only.

Melphalan is a chemotherapy agent that acts through alkylation of the DNA nucleotide guanine, and causes linkages between strands of DNA.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Melphalan is a chemotherapy agent that acts through alkylation of the DNA nucleotide guanine, and causes linkages between strands of DNA.
Melphalan inhibits DNA synthesis and RNA synthesis in both dividing and non-dividing tumor cells.

物理化学性质&存储条件

分子量 305.2002
分子式 C13H18Cl2N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: < 9.2 mg/mL
Chemical Name/SMILES

L-Phenylalanine, 4-[bis(2-chloroethyl)amino]-

参考文献

1. Dudek-Perić AM, et al. Cancer Res. 2015 Apr 15;75(8):1603-14.

2. Keane MM, et al. Cancer Res. 1999 Feb 1;59(3):734-41.

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