Magrolimab |CAS:2169232-81-7 Probechem Biochemicals

Chemical Structure : Magrolimab

CAS No.: 2169232-81-7

加入收藏

Magrolimab (Anti-human CD47 mAb, human IgG4-Kappa)

货号: PC-Ab1002Not For Human Use, Lab Use Only.

A monoclonal anti-human CD47 antibody by grafting its complementarity determining regions (CDRs) onto a human IgG4 format.

规格	价格	库存
1 mg	￥3580	In stock
5 mg	￥7580	In stock
10 mg	￥12800	In stock
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

A monoclonal anti-human CD47 antibody by grafting its complementarity determining regions (CDRs) onto a human IgG4 format; bound to monomeric human CD47 with an 8 nM affinity; induced potent macrophage-mediated phagocytosis of primary human AML cells in vitro and completely eradicated human AML in vivo, leading to long-term disease-free survival of patient-derived xenografts.

物理化学性质&存储条件

分子量
分子式	Human IgG4-Kappa
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES	Magrolimab; Hu5F9-G4; 5F9; 2169232-81-7; anti Leukocyte surface antigen CD47; Cluster of differentiation 47; CD47 Antigen (Rh-Related Antigen, Integrin-Associated Signal Transducer)

参考文献

1. 1, Sikic BI, et al. J Clin Oncol. 2019 Apr 20;37(12):946-953. 2, Advani R, et al. N Engl J Med. 2018 Nov 1;379(18):1711-1721. 3, Gholamin S, et al. Sci Transl Med. 2017 Mar 15;9(381):eaaf2968. 4, Liu J, et al. PLoS One. 2015 Sep 21;10(9):e0137345.

Magrolimab (Anti-human CD47 mAb, human IgG4-Kappa)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Magrolimab (Anti-human CD47 mAb, human IgG4-Kappa)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.