MY-5445 | PDE5 inhibitor | Probechem Biochemicals

Chemical Structure : MY-5445

CAS No.: 78351-75-4

加入收藏

MY-5445 (MY5445)

货号: PC-61344Not For Human Use, Lab Use Only.

MY-5445 is a specific PDE5 inhibitor that inhibits human platelet aggregation induced by 3 uM ADP, 3 mg/ml of collagen and 100 ug/ml of arachidonic acid with IC50 of 0.07, 0.02 and 0.17 uM, respectively.

规格	价格	库存
5 mg	￥880	In stock
10 mg	￥1280	In stock
25 mg	￥2180	In stock
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

MY-5445 is a specific PDE5 inhibitor that inhibits human platelet aggregation induced by 3 uM ADP, 3 mg/ml of collagen and 100 ug/ml of arachidonic acid with IC50 of 0.07, 0.02 and 0.17 uM, respectively.
MY-5445 shows no effect on either adenylate cyclase or guanylate cyclase activity.
MY-5445 inhibits human platelet aggregation by increasing cyclic GMP content.
MY-5445 is a useful probe for elucidating the role of cyclic GMP in platelet aggregation.

物理化学性质&存储条件

分子量	331.8
分子式	C20H14ClN3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-Chlorophenyl)-4-phenyl-1-phthalazinamine

参考文献

1. Yamamoto T, et al. J Biol Chem. 1983 Dec 10;258(23):14173-7.

2. Hagiwara M, et al. J Pharmacol Exp Ther. 1984 Feb;228(2):467-71.

3. Souness JE, et al. Br J Pharmacol. 1989 Nov;98(3):725-34.

MY-5445 (MY5445)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

MY-5445 (MY5445)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.