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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Chloride Channel-MT-189
MT-189

Chemical Structure : MT-189

CAS No.: 1014718-70-7

MT-189 (MT189)

货号: PC-27986Not For Human Use, Lab Use Only.

MT-189 is a specific small molecule inhibitor of chloride channel CLC-Ka (CLCNKA) with IC50 of 7.0 uM, 3-fold selectivity for CLC-Ka over CLC-Kb.

规格 价格 库存 数量
25 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MT-189 is a specific small molecule inhibitor of chloride channel CLC-Ka (CLCNKA) with IC50 of 7.0 uM, 3-fold selectivity for CLC-Ka over CLC-Kb.

物理化学性质&存储条件

分子量 307.13
分子式 C15H8Cl2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-chloro-3-(2-chlorophenyl)benzofuran-2-carboxylic acid

参考文献

1. Koster AK, et al. Proc Natl Acad Sci U S A. 2018 May 22;115(21):E4900-E4909.

2. Liantonio A, et al. J Hypertens. 2012 Jan;30(1):153-67.

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