MSA-2 dimer | STING agonist | Probechem Biochemicals

Chemical Structure : MSA-2 dimer

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MSA-2 dimer (diMSA-2)

货号: PC-26989Not For Human Use, Lab Use Only.

MSA-2 dimer (diMSA-2) is a selective, orally active non-nucleotide STING agonist with KD of 145 uM, binds to STING as a non-covalent dimer and exhibits long-term antitumor and immunogenic activity.

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生物&药学活性

MSA-2 dimer (diMSA-2) is a selective, orally active non-nucleotide STING agonist with KD of 145 uM, binds to STING as a non-covalent dimer and exhibits long-term antitumor and immunogenic activity.

物理化学性质&存储条件

分子量	568.66
分子式	C29H28O8S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4,4'-(Propane-1,3-diylbis(6-methoxybenzo[b]thiophene-5,2-diyl))bis(4-oxobutanoic acid)

参考文献

1. Pan BS, et al. An orally available non-nucleotide STING agonist with antitumor activity. Science. 2020;369(6506):eaba6098.

MSA-2 dimer (diMSA-2)

生物&药学活性

物理化学性质&存储条件

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MSA-2 dimer (diMSA-2)

生物&药学活性

物理化学性质&存储条件

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