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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-TRP Channel-MRTF-A-IN-2
MRTF-A-IN-2

Chemical Structure : MRTF-A-IN-2

CAS No.:

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MRTF-A-IN-2

货号: PC-28400Not For Human Use, Lab Use Only.

MRTF-A-IN-2 is a potent inhibitor of TRPM7-RhoA interaction, reduces reduced expression of the MRTF/SRF target genes TGF-β1 and TSPAN5, inhibiting cell proliferation and inducing senescence in HCC cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MRTF-A-IN-2 is a potent inhibitor of TRPM7-RhoA interaction, reduces reduced expression of the MRTF/SRF target genes TGF-β1 and TSPAN5, inhibiting cell proliferation and inducing senescence in HCC cells.

物理化学性质&存储条件

分子量 303.34
分子式 C19H14FN3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(3'-fluoro-[1,1'-biphenyl]-3-yl)-1H-benzo[d]imidazol-2-amine

参考文献

1. Franz MJ, et al. Mol Ther Oncol. 2024 Aug 6;32(3):200855.

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