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首页-小分子抑制剂&激动剂-GPCR-Adenosine Receptor-MRS1523
MRS1523

Chemical Structure : MRS1523

CAS No.: 212329-37-8

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MRS1523 (MRS 1523, MRS-1523)

货号: PC-28428Not For Human Use, Lab Use Only.

MRS1523 (MRS 1523) is a potent and selective adenosine A3 receptor (A3AR) antagonist with Ki of 18.9 nM and 113 nM for human and rat A3 receptors, respectively. 

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

MRS1523 (MRS 1523) is a potent and selective adenosine A3 receptor (A3AR) antagonist with Ki of 18.9 nM and 113 nM for human and rat A3 receptors, respectively. 
MRS1523 shows 140- and 18-fold selectivities over A1 and A2A receptors, respectively.

物理化学性质&存储条件

分子量 399.55
分子式 C23H29NO3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Propyl 6-ethyl-5-((ethylthio)carbonyl)-2-phenyl-4-propylnicotinate

参考文献

1. Li AH, et al.J Med Chem. 1998 Aug 13;41(17):3186-201.

2. Coppi E, et al. 2019 May;160(5):1103-1118.

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