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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-GABA Receptor-MRK-623
MRK-623

Chemical Structure : MRK-623

CAS No.: 461449-78-5

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MRK-623 (MRK623)

货号: PC-62770Not For Human Use, Lab Use Only.

MRK-623 is a potent, α2/α3 subunit functionally selectivie GABAA receptor agonist with Ki values of 0.85 nM, 3.7 nM, 4.0 nM, and 0.53 nM for α1, α2, α3, and α5, respectively.

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纯度 & COA & 质检文件 纯度: 99.14% (HPLC) Select Batch:

生物&药学活性

MRK-623 is a potent, α2/α3 subunit functionally selectivie GABAA receptor agonist with Ki values of 0.85 nM, 3.7 nM, 4.0 nM, and 0.53 nM for α1, α2, α3, and α5, respectively.

物理化学性质&存储条件

分子量 348.381
分子式 C20H17FN4O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(3-(4-fluoro-3-pyridin-3-yl-phenyl)-imidazo(1,2-a)pyrimidin-7-yl)-propan-2-ol

参考文献

1. Shinday NM, et al. Neuropsychopharmacology. 2013 May;38(6):1006-14.

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