MPT-0118 | MALT1 inhibitor | Probechem Biochemicals

Chemical Structure : MPT-0118

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MPT-0118 ((S)-mepazine succinate)

货号: PC-25810Not For Human Use, Lab Use Only.

MPT-0118 ((S)-mepazine succinate) is a potent, selective MALT1 paracaspase inhibitor with IC50 of 0.26 uM, has approximately 10-fold greater MALT1 inhibitory activity than (R)-mepazine.

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生物&药学活性

MPT-0118 ((S)-mepazine succinate) is a potent, selective MALT1 paracaspase inhibitor with IC50 of 0.26 uM, has approximately 10-fold greater MALT1 inhibitory activity than (R)-mepazine.

物理化学性质&存储条件

分子量	428.55
分子式	C23H28N2O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-10-((1-methylpiperidin-3-yl)methyl)-10H-phenothiazine succinate

参考文献

1. Di Pilato M, et al. J Immunother Precis Oncol. 2023 Mar 3;6(2):61-73.

2. Schlauderer F, et al. Structural analysis of phenothiazine derivatives as allosteric inhibitors of the MALT1 paracaspase. Angew Chem Int Ed Engl . 2013;52:10384–10387.

MPT-0118 ((S)-mepazine succinate)

生物&药学活性

物理化学性质&存储条件

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MPT-0118 ((S)-mepazine succinate)

生物&药学活性

物理化学性质&存储条件

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