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首页-小分子抑制剂&激动剂-Others-Other Targets-MP-002
MP-002

Chemical Structure : MP-002

CAS No.: 2161432-00-2

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MP-002 (AHK2)

货号: PC-28594Not For Human Use, Lab Use Only.

MP-002 (AHK2) is a triazole-based FKBP12 ligand, competes with rapamycin for the FKBP12 binding pocket, stabilizing the FKBP12/RyR interaction, rescues multiple premature aging phenotypes in dyotonic dystrophy type 1 (DM1) models.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MP-002 (AHK2) is a triazole-based FKBP12 ligand, competes with rapamycin for the FKBP12 binding pocket, stabilizing the FKBP12/RyR interaction, rescues multiple premature aging phenotypes in dyotonic dystrophy type 1 (DM1) models.

物理化学性质&存储条件

分子量 292.40
分子式 C14H20N4OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-[2-(N,N-dimethylamino)ethyl]-4-[(4-methoxyphenyl)thiomethyl]-1H-1,2,3-triazole

参考文献

1. Passannante R, et al. Biomedicines. 2023 Jan 18;11(2):253.

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