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首页-小分子抑制剂&激动剂-Epigenetics-Histone Acetyltransferase (HAT)-MOZ-IN-3
MOZ-IN-3

Chemical Structure : MOZ-IN-3

CAS No.: 3059058-07-7

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MOZ-IN-3 (KAT6A inhibitor 6j)

货号: PC-27554Not For Human Use, Lab Use Only.

MOZ-IN-3 (KAT6A inhibitor 6j) is a potent, selective inhibitor of KAT6A (MOZ, Monocytic leukemia zinc finger protein) with IC50 of 0.03 uM, shows 25-333 fold selectivity against KAT7, KAT5, KAT8 and KAT6B, exhibitsstrong antitumor activity on leukemia cell line K562 (IC50=82 nM).

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10 mg ￥880 In stock
25 mg ￥1280 In stock
50 mg ￥1980 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

MOZ-IN-3 (KAT6A inhibitor 6j) is a potent, selective inhibitor of KAT6A (MOZ, Monocytic leukemia zinc finger protein) with IC50 of 0.03 uM, shows 25-333 fold selectivity against KAT7, KAT5, KAT8 and KAT6B, exhibitsstrong antitumor activity on leukemia cell line K562 (IC50=82 nM).

物理化学性质&存储条件

分子量 344.36
分子式 C17H13FN2O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(2-(2-fluorophenyl)-2-oxoethyl)quinoline-8-sulfonamide

参考文献

1. Yongtao Duan, et al. Eur J Med Chem. 2023 Nov 15:260:115770.

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