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首页-小分子抑制剂&激动剂-GPCR-Cannabinoid Receptor-MN-25
MN-25

Chemical Structure : MN-25

CAS No.: 501926-82-5

MN-25 (CB2 agonist MN25;AR-12;AR12)

货号: PC-60758Not For Human Use, Lab Use Only.

CB2 agonist MN25 (AR12) is a potent, reasonably selective agonist of peripheral cannabinoid receptor with Ki of 11 nM for CB2, 22-fold selectivity over the psychoactive CB1 receptors (Ki=245 nM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    CB2 agonist MN25 (AR12) is a potent, reasonably selective agonist of peripheral cannabinoid receptor with Ki of 11 nM for CB2, 22-fold selectivity over the psychoactive CB1 receptors (Ki=245 nM).

    物理化学性质&存储条件

    分子量 439.59
    分子式 C26H37N3O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-[(S)-Fenchyl]-1-[2-(morpholin-4-yl)ethyl]-7-methoxyindole-3-carboxamide

    参考文献

    1. Wrobleski ST, et al. J Med Chem. 2003 May 22;46(11):2110-6.

    2. Hynes J Jr, et al. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2399-402.

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