MMV1580853 (BPH-1358) | Antimalarial | Probechem Biochemicals

Chemical Structure : MMV1580853

CAS No.: 5352-53-4

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MMV1580853 (BPH-1358, MMV 1580853)

货号: PC-22743Not For Human Use, Lab Use Only.

MMV1580853 (BPH-1358) is a potent and exceedingly fast-acting blood-stage antimalarial, inhibits human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor with IC50s of 1.8 μM and 110 nM, respectively, is active against S. aureus in vitro (MIC, 250 ng/mL).

规格	价格	库存
5 mg	￥1280	In stock
10 mg	￥1980	In stock
25 mg	￥3580	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

MMV1580853 (BPH-1358) is a potent and exceedingly fast-acting blood-stage antimalarial, inhibits human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor with IC50s of 1.8 μM and 110 nM, respectively, is active against S. aureus in vitro (MIC, 250 ng/mL).

物理化学性质&存储条件

分子量	601.53
分子式	C32H30Cl2N6O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N4,N4'-bis(3-(4,5-dihydro-1H-imidazol-2-yl)phenyl)-[1,1'-biphenyl]-4,4'-dicarboxamide dihydrochloride

参考文献

1. Ryan Choi, et al. PLoS One. 2021 Apr 22;16(4):e0250019.

2. Zhu W, et al. J Med Chem. 2015 Feb 12;58(3):1215-27.

MMV1580853 (BPH-1358, MMV 1580853)

生物&药学活性

物理化学性质&存储条件

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MMV1580853 (BPH-1358, MMV 1580853)

生物&药学活性

物理化学性质&存储条件

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