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首页-小分子抑制剂&激动剂-Apoptosis-Caspase-MMPSI
MMPSI

Chemical Structure : MMPSI

CAS No.: 220509-74-0

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MMPSI (Caspase 3/7 inhibitor MPS)

货号: PC-24912Not For Human Use, Lab Use Only.

MMPSI is a potent and selective, non-peptide caspase 3/7 inhibitor with Ki app of 0.06 uM and 0.17 uM respective, exhibits >100-fold selectivity over all other family members except caspase 9 (Ki app=3.1 uM).

规格 价格 库存 数量
5 mg ￥2180 In stock
10 mg ￥3580 In stock
25 mg ￥5980 In stock
50 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

MMPSI is a potent and selective, non-peptide caspase 3/7 inhibitor with Ki app of 0.06 uM and 0.17 uM respective, exhibits >100-fold selectivity over all other family members except caspase 9 (Ki app=3.1 uM).

物理化学性质&存储条件

分子量 324.35
分子式 C14H16N2O5S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-5-((2-(Methoxymethyl)pyrrolidin-1-yl)sulfonyl)indoline-2,3-dione

参考文献

1. Chapman JG, et al, Eur J Pharmacol. 2002;456(1-3):59-68.

2. Lee D, et al. J Biol Chem. 2000 May 26;275(21):16007-14.

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