MMPIP hydrochloride

Chemical Structure : MMPIP hydrochloride

CAS No.: 1215566-78-1

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货号: PC-22271Not For Human Use, Lab Use Only.

MMPIP hydrochloride is a selective, allosteric metabotropic glutamate receptor 7 (mGluR7) antagonist / negative allosteric modulator with Kb value of 24-30 nM.

规格	价格	库存
5 mg	￥1280	In stock
10 mg	￥1980	In stock
25 mg	￥3480	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

MMPIP hydrochloride is a selective, allosteric metabotropic glutamate receptor 7 (mGluR7) antagonist / negative allosteric modulator with Kb value of 24-30 nM.
MMPIP hydrochloride reversed antidepressant-like effects of AMN082 in rats.
MMPIP hydrochloride alleviates pain and normalizes affective and cognitive behavior in neuropathic mice.

物理化学性质&存储条件

分子量	369.81
分子式	C19H16ClN3O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	6-(4-methoxyphenyl)-5-methyl-3-pyridin-4-ylisoxazolo[4,5-c]pyridin-4(5H)-one hydrochloride

参考文献

1. Kotlinska JH, et al. Eur J Pharmacol. 2019 Sep 5;858:172512.

2. Palazzo E, et al. Pain. 2015 Jun;156(6):1060-1073.

3. Pałucha-Poniewiera A, et al. Behav Brain Res. 2013 Feb 1;238:109-12.