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首页-小分子抑制剂&激动剂-GPCR-mAChR-ML293
ML293

Chemical Structure : ML293

CAS No.: 1393492-05-1

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ML293

货号: PC-24345Not For Human Use, Lab Use Only.

ML293 is a selective, brain penetrant M4 mAChR positive allosteric modulator (PAM) with EC50 of 1.3M (hM4), selective against the four other muscarinic subtypes.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

ML293 is a selective, brain penetrant M4 mAChR positive allosteric modulator (PAM) with EC50 of 1.3M (hM4), selective against the four other muscarinic subtypes.

物理化学性质&存储条件

分子量 299.35
分子式 C15H13N3O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(4-methoxy-7-methylbenzo[d]thiazol-2-yl)isonicotinamide

参考文献

1. Salovich JM, et al. Bioorg Med Chem Lett. 2012 Aug 1;22(15):5084-8.

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