欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Potassium Channel-ML213
ML213

Chemical Structure : ML213

CAS No.: 489402-47-3

加入收藏

ML213 (ML-213, ML 213)

货号: PC-60228Not For Human Use, Lab Use Only.

ML213 is a potent, selective KCNQ2 (Kv7.2) and KCNQ4 (Kv7.4) activator with EC50 of 230 and 510 nM, respectively.

规格 价格 库存 数量
10 mg ￥780 In stock
25 mg ￥1380 In stock
50 mg ￥2180 In stock
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ML213 is a potent, selective KCNQ2 (Kv7.2) and KCNQ4 (Kv7.4) activator with EC50 of 230 and 510 nM, respectively.
ML213 displays >80-fold selectivity over other related potassium channels (KCNQ1/3/5).
ML213 causes significant hyperpolarization in mesenteric artery smooth muscle cells, shows potent vasorelaxant effects in different blood vessels.

物理化学性质&存储条件

分子量 257.37
分子式 C17H23NO
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(2,4,6-Trimethylphenyl)-bicyclo[2.2.1]heptane-2-carboxamide

参考文献

1. Yu H, et al. ACS Chem Neurosci. 2011 Oct 19;2(10):572-577.

2. Jepps TA, et al. Br J Pharmacol. 2014 Oct;171(19):4413-24.

3. Brueggemann LI, et al. Mol Pharmacol. 2014 Sep;86(3):330-41.

4. Provence A, et al. J Pharmacol Exp Ther. 2017 Oct 30. pii: jpet.117.243162.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: