ML-241 hydrochloride |CAS: 2070015-13-1 Probechem Biochemicals

Chemical Structure : ML-241 hydrochloride

CAS No.: 2070015-13-1

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ML-241 hydrochloride (ML241 hydrochloride;ML 241 hydrochloride)

货号: PC-45719Not For Human Use, Lab Use Only.

ML241 hydrochloride is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM).

规格	价格	库存
25 mg	￥1580	In stock
50 mg	￥2480	In stock
100 mg	￥3980	In stock
200 mg		Get quote
1 g		Get quote

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生物&药学活性

ML241 hydrochloride is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM).
ML241 blocks degradation of p97-dependent proteasome substrate with an IC50 of 3.5 uM.
ML241 induces caspases 3 and 7 and potently blocks proliferation in HCT15 and SW403 cells.

物理化学性质&存储条件

分子量	408.9238
分子式	C23H25ClN4O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	DMSO: ≥ 34 mg/mL
Chemical Name/SMILES	4-Quinazolinamine, 2-(2,3-dihydro-4H-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydro-N-(phenylmethyl)-,hydrochloride

参考文献

1. Chou TF, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].

2. Chou TF, et al. ChemMedChem. 2013 Feb;8(2):297-312.

3. Fang CJ, et al. ChemMedChem. 2015 Jan;10(1):52-6.

ML-241 hydrochloride (ML241 hydrochloride;ML 241 hydrochloride)

生物&药学活性

物理化学性质&存储条件

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ML-241 hydrochloride (ML241 hydrochloride;ML 241 hydrochloride)

生物&药学活性

物理化学性质&存储条件

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