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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Aldose Reductase-MK204
MK204

Chemical Structure : MK204

CAS No.: 1959605-73-2

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MK204 (MK-204)

货号: PC-62883Not For Human Use, Lab Use Only.

MK204 is a potent, selective AKR1B10 inhibitor with IC50 of 80 nM, shows high selective (270-fold) over AKR1B1.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    MK204 is a potent, selective AKR1B10 inhibitor with IC50 of 80 nM, shows high selective (270-fold) over AKR1B1.
    MK204 is a lead compound targeting the distinct AKR1B10 specificity pocket and with a strong X-bond.

    物理化学性质&存储条件

    分子量 714.221
    分子式 C16H9Br5ClNO4
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    Acetic acid, 2-[5-chloro-2-[[[(2,3,4,5,6-pentabromophenyl)methyl]amino]carbonyl]phenoxy]-

    参考文献

    1. Cousido-Siah A, et al. ACS Chem Biol. 2016 Oct 21;11(10):2693-2705.

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