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首页-小分子抑制剂&激动剂-PI3K/Akt/mTOR Pathway-PI3K-MIPS-19417
MIPS-19417

Chemical Structure : MIPS-19417

CAS No.: 2001083-66-3

MIPS-19417 (MIPS19417)

货号: PC-25114Not For Human Use, Lab Use Only.

MIPS-19417 is a potent, selective PI3KC2β inhibitor with IC50 of 278 nM, does not inhibit PI3KC2α (IC50>10 uM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MIPS-19417 is a potent, selective PI3KC2β inhibitor with IC50 of 278 nM, does not inhibit PI3KC2α (IC50>10 uM).

物理化学性质&存储条件

分子量 527.58
分子式 C25H31F2N9O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-(4-(4-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-yl)-6-morpholino-1,3,5-triazin-2-yl)piperazin-1-yl)(piperidin-2-yl)methanone

参考文献

1. Maria V Selvadurai, et al. Sci Transl Med. 2020 Jul 22;12(553):eaar8430.

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