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首页-抗体和重组蛋白-Biosimilar Antibody-MDX-1342
MDX-1342

Chemical Structure : MDX-1342

CAS No.:

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MDX-1342 (Anti-human CD19 mAb, human IgG1-Kappa)

货号: PC-Ab1074Not For Human Use, Lab Use Only.

MDX-1342 is a fully human monoclonal antibody with enhanced antibody-dependent cellular cytotoxicity (ADCC) effector function, targeting CD19-membrane receptor which is highly expressed on malignant chronic lymphocytic leukemia (CLL) cells. MDX-1342 blocks activation of B cell stimulation, decreasing the number of cancerous B cell clones..

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1 mg ￥3580 In stock
5 mg ￥7580 In stock
10 mg ￥12800 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

MDX-1342 is a fully human monoclonal antibody with enhanced antibody-dependent cellular cytotoxicity (ADCC) effector function, targeting CD19-membrane receptor which is highly expressed on malignant chronic lymphocytic leukemia (CLL) cells. MDX-1342 blocks activation of B cell stimulation, decreasing the number of cancerous B cell clones.

物理化学性质&存储条件

分子量
分子式 Human IgG1-Kappa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES

MDX-1342; MDX1342; Anti-human CD19; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; T-cell surface antigen Leu-12; differentiation antigen CD19

参考文献

1. 1, Pina M Cardarelli, et al. Cancer Immunol Immunother. 2010 Feb;59(2):257-65.

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