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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-NADPH Oxidase (NOX)-MC4876
MC4876

Chemical Structure : MC4876

CAS No.: 3144317-24-5

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MC4876 (MC-4876)

货号: PC-28569Not For Human Use, Lab Use Only.

MC4876 is a potent, selective NADPH oxidase 2 (NOX2) inhibitor with IC50 of 7.7 uM (hNOX2), shows much weaker acitivty against hNOX1 (71.2 uM), hNOX4 (81.2 uM) and hNOX5 (28 uM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MC4876 is a potent, selective NADPH oxidase 2 (NOX2) inhibitor with IC50 of 7.7 uM (hNOX2), shows much weaker acitivty against hNOX1 (71.2 uM), hNOX4 (81.2 uM) and hNOX5 (28 uM).

物理化学性质&存储条件

分子量 303.41
分子式 C20H21N3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-phenyl-N-(piperidin-4-yl)quinolin-2-amine

参考文献

1. Chiara Lambona, et al. J Med Chem. 2026 Oct 22;69(20):24557-24585.

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