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首页-小分子抑制剂&激动剂-GPCR-Melanocortin Receptor-MC4-NN2-0453
MC4-NN2-0453

Chemical Structure : MC4-NN2-0453

CAS No.: 1228015-10-8

MC4-NN2-0453

货号: PC-26944Not For Human Use, Lab Use Only.

MC4-NN2-0453 is a potent, long-acting, selective, peptide melanocortin-4 receptor (MC4R) agonist, >1000-fold selective over MC1R.

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1 mg ¥2280 In stock
5 mg ¥5280 In stock
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25 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

MC4-NN2-0453 is a potent, long-acting, selective, peptide melanocortin-4 receptor (MC4R) agonist, >1000-fold selective over MC1R.

物理化学性质&存储条件

分子量 2092.36
分子式 C96H146N28O25
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

L-Lysinamide, N-[2-[2-[2-[[1-oxo-16-(2H-tetrazol-5-yl)hexadecyl]amino]ethoxy]ethoxy]acetyl]glycyl-L-seryl-L-glutaminyl-L-histidyl-3-[[2-[bis(carboxymethyl)amino]acetyl]amino]-L-alanyl-L-norleucyl-L-α-glutamyl-(4R)-4-hydroxy-L-prolyl-D-phenylalanyl-L-arginyl-L-tryptophyl-, (7→12)-lactam

参考文献

1. Kilian Conde-Frieboes, et al. J Med Chem. 2012 Mar 8;55(5):1969-77.

2. Jane E Royalty, et al. J Clin Pharmacol. 2014 Apr;54(4):394-404.

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