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首页-小分子抑制剂&激动剂-Others-Other Targets-MBTP-15324
MBTP-15324

Chemical Structure : MBTP-15324

CAS No.: 924822-67-3

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MBTP-15324 (MBTP15324)

货号: PC-27843Not For Human Use, Lab Use Only.

MBTP-15324 is an allosteric inhibitor of proline dehydrogenase (PRODH) with Kd of 1.45 uM, significantly attenuates cell viability, colony formation, and migration in PRODH-overexpressing lung cancer cells (A549 and LLC).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MBTP-15324 is an allosteric inhibitor of proline dehydrogenase (PRODH) with Kd of 1.45 uM, significantly attenuates cell viability, colony formation, and migration in PRODH-overexpressing lung cancer cells (A549 and LLC).

物理化学性质&存储条件

分子量 386.47
分子式 C20H22N2O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-hydroxy-1-(2-((2-hydroxyethyl)amino)ethyl)-4-(4-methylbenzoyl)-5-(thiophen-2-yl)-1,5-dihydro-2H-pyrrol-2-one

参考文献

1. Yuxuan Zhou, et al. J Enzyme Inhib Med Chem. 2026 Dec;41(1):2719719.

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