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首页-小分子抑制剂&激动剂-Others-Other Targets-MASTL inhibitor 16
MASTL inhibitor 16

Chemical Structure : MASTL inhibitor 16

CAS No.: 3024916-69-3

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MASTL inhibitor 16

货号: PC-23351Not For Human Use, Lab Use Only.

MASTL inhibitor 16 is a potent, highly selective inhibitor of microtubule-associated serine/threonine kinase-like (MASTL, Greatwall) with Ki of 0.12 nM, cellular pENSA IC50 of 2.8 nM in MDA-MB-231 cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MASTL inhibitor 16 is a potent, highly selective inhibitor of microtubule-associated serine/threonine kinase-like (MASTL, Greatwall) with Ki of 0.12 nM, cellular pENSA IC50 of 2.8 nM in MDA-MB-231 cells.

物理化学性质&存储条件

分子量 421.51
分子式 C22H27N7O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-(6-((8-amino-6-methyl-2,7-naphthyridin-3-yl)amino)-4-(3-aminopentan-3-yl)pyridin-2-yl)oxazolidin-2-one

参考文献

1. Gallego RA, et al. J Med Chem. 2024 Nov 5. doi: 10.1021/acs.jmedchem.4c01659.

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