MASP-2, MASP-3 dual inhibitor 45

Chemical Structure : MASP-2, MASP-3 dual inhibitor 45

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货号: PC-24088Not For Human Use, Lab Use Only.

MASP-2, MASP-3 dual inhibitor 45 is a potent, dual inhibitor of mannan-binding lectin-associated serine protease MASP-2 and MASP-3 with IC50 of 7.5 nM and 33 nM respectively.

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生物&药学活性

MASP-2, MASP-3 dual inhibitor 45 is a potent, dual inhibitor of mannan-binding lectin-associated serine protease MASP-2 and MASP-3 with IC50 of 7.5 nM and 33 nM respectively.

物理化学性质&存储条件

分子量	491.57
分子式	C25H25N5O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-(2-amino-1H-imidazole-4-yl)-3-methoxybenzyl)-2-(4-(phenylsulfonamido)phenyl) acetamide

参考文献

1. Nakhla MC, et al. Eur J Med Chem. 2025 Jan 9;289:117238.