Chemical Structure : M7824
CAS No.:
货号: PC-Ab1007Not For Human Use, Lab Use Only.
Bintrafusp alfa (M7824), a bifunctional fusion protein targeting TGF-β and PD-L1, attenuated features of TGF-β1-mediated mesenchymalization, including mesenchymal marker expression, proliferation suppression, and chemoresistance in vitro and in vivo..
| 规格 | 价格 | 库存 | 数量 | 
|---|---|---|---|
| 1 mg | ¥3580 | In stock | |
| 5 mg | ¥7580 | In stock | |
| 10 mg | ¥12800 | In stock | |
| 100 mg | Get quote | 
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Bintrafusp alfa (M7824), a bifunctional fusion protein targeting TGF-β and PD-L1, attenuated features of TGF-β1-mediated mesenchymalization, including mesenchymal marker expression, proliferation suppression, and chemoresistance in vitro and in vivo.
| 分子量 | ||
| 分子式 | Human IgG1-Kappa | |
| 外观性状 | Solid | |
| 储存条件 | 
                            
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| Solubility | 
                             PBS, pH 7.0 Contains no stabilizers or preservatives  | 
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| Chemical Name/SMILES | 
                             M7824; MSB0011359C; MSB 0011359C; Bintrafusp alfa; Anti-human PD-L1; programmed death 1 Ligand; Anti-human TGFBR2 (Transforming Growth Factor Beta Receptor 2); PD-L1, TGFβR2 bispecific  | 
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1. 1, Knudson KM, et al. Oncoimmunology. 2018 Feb 14;7(5):e1426519. 2, David JM, et al. Oncoimmunology. 2017 Jul 13;6(10):e1349589. 3, Jochems C, et al. Oncotarget. 2017 Sep 8;8(43):75217-75231.
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