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首页-小分子抑制剂&激动剂-TGF-beta/Smad-TGF beta Receptor (TGFBR)-M4K2308
M4K2308

Chemical Structure : M4K2308

CAS No.: 3034840-18-8

M4K2308

货号: PC-26694Not For Human Use, Lab Use Only.

M4K2308 is a potent, selective inhibitor of ALK2 with IC50 of 2 nM, >100-fold selectivity over ALK5.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

M4K2308 is a potent, selective inhibitor of ALK2 with IC50 of 2 nM, >100-fold selectivity over ALK5.

物理化学性质&存储条件

分子量 447.54
分子式 C26H29N3O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

[1]Benzoxepino[5,4-c]pyridine, 5,6-dihydro-9-(1-piperazinyl)-4-(3,4,5-trimethoxyphenyl)-

参考文献

1. Héctor González-Álvarez, et al. J Med Chem. 2024 Mar 28;67(6):4707-4725.

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