M4K2163 dihydrochloride

Chemical Structure : M4K2163 dihydrochloride

CAS No.: 2863635-04-3

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货号: PC-26693Not For Human Use, Lab Use Only.

M4K2163 dihydrochloride is a potent, selective, blood-brain barrier (BBB) permeable activin receptor-like kinase-2 (ALK2) inhibitor with IC50 of 19 nM.

规格	价格	库存
5 mg	￥980	In stock
10 mg	￥1480	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

M4K2163 dihydrochloride is a potent, selective, blood-brain barrier (BBB) permeable activin receptor-like kinase-2 (ALK2) inhibitor with IC50 of 19 nM.

物理化学性质&存储条件

分子量	480.41
分子式	C24H28Cl2FN3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(4-(5-(4-fluoro-3,5-dimethoxyphenyl)-4-methylpyridin-3-yl)phenyl)piperazine dihydrochloride

参考文献

1. Smil D, et al. J Med Chem. 2020 Sep 10;63(17):10061-10085.

2. Rooney L, et al. ACS Omega. 2021 Aug 6;6(32):20729-20734.