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首页-小分子抑制剂&激动剂-Immunology/Inflammation-Nitric Oxide Synthase (NOS)-Lubeluzole
Lubeluzole

Chemical Structure : Lubeluzole

CAS No.: 144665-07-6

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Lubeluzole

货号: PC-25065Not For Human Use, Lab Use Only.

Lubeluzole is a neuroprotective agent displaying antimyotonic activity, inhibits glutamate-stimulated guanosine 3',5'-cyclic monophosphate production with IC50 of 37 nM, inhibits the glutamate-activated nitric oxide synthase pathway.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Lubeluzole is a neuroprotective agent displaying antimyotonic activity, inhibits glutamate-stimulated guanosine 3',5'-cyclic monophosphate production with IC50 of 37 nM, inhibits the glutamate-activated nitric oxide synthase pathway.

物理化学性质&存储条件

分子量 433.52
分子式 C22H25F2N3O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-1-(4-(benzo[d]thiazol-2-yl(methyl)amino)piperidin-1-yl)-3-(3,4-difluorophenoxy)propan-2-ol

参考文献

1. Lesage AS, et al. J Pharmacol Exp Ther. 1996 Nov;279(2):759-66.

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