Lipoamide | CAS 940-69-2 | Probechem Biochemicals

Chemical Structure : Lipoamide

CAS No.: 940-69-2

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Lipoamide ((±)-α-Lipoamide)

货号: PC-24660Not For Human Use, Lab Use Only.

规格	价格	库存
100 mg	￥280	In stock
500 mg	￥580	In stock
1 g	￥880	In stock
2 g		Get quote

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生物&药学活性

Lipoamide (Alpha-lipoamide) is a neutral derivative of lipoic acid with antioxidant and organ-protective properties, specifically prevents cytoplasmic condensation of stress granule proteins including SRSF1 and SFPQ.
Lipoamide (LAM) has been widely studied as an agent for alleviating various diseases associated with oxidative disruption.
Lipoamide ameliorates aging-associated aggregation of a stress granule reporter protein, improves neuronal morphology and recovers motor defects caused by amyotrophic lateral sclerosis-associated FUS and TDP-43 mutants.

物理化学性质&存储条件

分子量	205.33
分子式	C8H15NOS2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(1,2-Dithiolan-3-yl)pentanamide

参考文献

1. Uechi H, Nat Chem Biol. 2025 May 14. doi: 10.1038/s41589-025-01893-5.

2. Tan WL, et al. Biochem Pharmacol. 2025 Apr 12;237:116942.

Lipoamide ((±)-α-Lipoamide)

生物&药学活性

物理化学性质&存储条件

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Lipoamide ((±)-α-Lipoamide)

生物&药学活性

物理化学性质&存储条件

参考文献

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