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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Calcium Channel -Linoleamide
Linoleamide

Chemical Structure : Linoleamide

CAS No.: 3999-01-7

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Linoleamide (Linoleic acid amide)

货号: PC-27044Not For Human Use, Lab Use Only.

Linoleamide is an endogenous lipid which is structurally related to sphingosine and sphiganine and closely related with sarco/endoplasmic reticulum Ca2+‐ATPase (SERCA) activity, increases cytosolic Ca2+ levels in MDCK with EC50 of 20 uM.

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50 mg ￥2580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Linoleamide is an endogenous lipid which is structurally related to sphingosine and sphiganine and closely related with sarco/endoplasmic reticulum Ca2+‐ATPase (SERCA) activity, increases cytosolic Ca2+ levels in MDCK with EC50 of 20 uM.
Linoleamide has been shown to induce sleep in cats, rats and humans.
Linoleamide inhibits Ca2+-ATPase activity of each SERCA with IC50 of 15-53 uM.

物理化学性质&存储条件

分子量 279.47
分子式 C18H33NO
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(9Z,12Z)-octadeca-9,12-dienamide

参考文献

1. J K Huang, et al. Life Sci. 2001 Jan 19;68(9):997-1004.

2. Sachiko Yamamoto, et al. Biochim Biophys Acta Gen Subj. 2017 Jan;1861(1 Pt A):3399-3405.

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