Licoflavone B

Chemical Structure : Licoflavone B

CAS No.: 91433-17-9

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货号: PC-25607Not For Human Use, Lab Use Only.

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5 mg	￥2480	In stock
10 mg	￥3980	In stock
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100 mg		Get quote

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生物&药学活性

Licoflavone B is an isoprene flavonoid derived from licorice residue and potent anti-influenza agent, selectively targets the viral RNA-dependent RNA polymerase (RdRp) with IC50 of 9.9 uM, effectively suppressing viral replication, also exerts anti-ulcerative colitis (UC) activity through blocking the MAPK pathway.
Licoflavone B demonstrates significant antiviral activity of licoflavone B against the influenza virus with IC50 of 6.7 uM against A/Puerto Rico/8/34 (H1N1).
Licoflavone B has a stable inhibitory effect against A/Puerto Rico/8/34 (H1N1) at 24, 48, and 72 hpi, with IC50 values of 5.4, 12.1, and 12.4 μM, respectively.
Licoflavone B shows broad inhibitory activity against A/Puerto Rico/8/34 (H1N1), followed by A/Darwin/9/2021 (H3N2).

物理化学性质&存储条件

分子量	390.48
分子式	C25H26O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	7-Hydroxy-2-(4-hydroxy-3-(3-methylbut-2-en-1-yl)phenyl)-6-(3-methylbut-2-en-1-yl)-4H-chromen-4-one

参考文献

1. Zhang J, et al. Eur J Pharmacol. 2022 Feb 5;916:174730.

2. Fan P, et al. Viruses. 2025 Aug 24;17(9):1157.

3. Grienke U, et al. J Nat Prod. 2014 Mar 28;77(3):563-70.

Licoflavone B

生物&药学活性

物理化学性质&存储条件

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Licoflavone B

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物理化学性质&存储条件

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