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首页-抗体和重组蛋白-Biosimilar Antibody-Lebrikizumab
Lebrikizumab

Chemical Structure : Lebrikizumab

CAS No.: 953400-68-5

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Lebrikizumab (Anti-human IL-13 mAb, human IgG4P-Kappa; LY-3650150)

货号: PC-Ab1053Not For Human Use, Lab Use Only.

Lebrikizumab is a novel high-affinity monoclonal antibody targeting IL-13 that selectively blocks the IL-13 receptor α1 (IL-13Rα1) and IL-4Rα heterodimer signaling complex. Lebrikizumab shows high bioavailability, a long half-life and blocks IL-13 signaling..

规格 价格 库存 数量
1 mg ￥3580 In stock
5 mg ￥7580 In stock
10 mg ￥12800 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Lebrikizumab is a novel high-affinity monoclonal antibody targeting IL-13 that selectively blocks the IL-13 receptor α1 (IL-13Rα1) and IL-4Rα heterodimer signaling complex. Lebrikizumab shows high bioavailability, a long half-life and blocks IL-13 signaling.

物理化学性质&存储条件

分子量
分子式 Human IgG4P-Kappa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES

Lebrikizumab; DRM-06; LY-3650150; MILR1444A; MILR1444Ab; RG-3637; RO-5490255; TNX 650; 953400-68-5; Interleukin 13 signaling; IL-13 antibody

参考文献

1. 1, Guttman-Yassky E, et al. JAMA Dermatol. 2020 Apr 1;156(4):411-420.  2, Simpson EL, et al. J Am Acad Dermatol. 2018 May;78(5):863-871.e11. 3, Loh TY, et al. J Asthma Allergy. 2020 Feb 11;13:109-114.  4, Corren J, et al. N Engl J Med. 2011 Sep 22;365(12):1088-98.

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