Lavengratinib (ABSK061) | FGFR2/3 inhibitor | Probechem Biochemicals

Chemical Structure : Lavengratinib

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Lavengratinib (ABSK061, ABSK-061)

货号: PC-27469Not For Human Use, Lab Use Only.

Lavengratinib (ABSK061) is a potent, highly selective oral FGFR2/3 inhibitor, including secondary FGFR2/3 kinase domain mutations as well as off-target alterations in RTK/RAS and DDR pathways.

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Lavengratinib (ABSK061) is a potent, highly selective oral FGFR2/3 inhibitor, including secondary FGFR2/3 kinase domain mutations as well as off-target alterations in RTK/RAS and DDR pathways.

物理化学性质&存储条件

分子量	544.43
分子式	C26H27Cl2N5O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-methyl-7-(1-(2-morpholinoethyl)-1H-pyrazol-4-yl)-1,6-naphthyridin-2(1H)-one

参考文献

1. Patent WO2020052349 A1 2020-03-19.

2. Yue Wang, et al. Cancer Res (2026) 86 (7_Supplement): 5319.

Lavengratinib (ABSK061, ABSK-061)

生物&药学活性

物理化学性质&存储条件

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Lavengratinib (ABSK061, ABSK-061)

生物&药学活性

物理化学性质&存储条件

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