Lalistat-1 (Lalistat 1)

Chemical Structure : Lalistat-1

CAS No.: 501104-16-1

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货号: PC-20890Not For Human Use, Lab Use Only.

Lalistat 1 (Lalistat 1) is a potent and selective lysosomal acid lipase (LAL) inhibitor with IC50 of 68 nM, shows no significant activity against pancreatic lipase or lipoprotein lipase.

规格	价格	库存
5 mg	￥880	In stock
10 mg	￥1280	In stock
25 mg	￥2180	In stock
50 mg	￥3480	In stock
100 mg		Get quote

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生物&药学活性

Lalistat 1 (Lalistat 1) is a potent and selective lysosomal acid lipase (LAL) inhibitor with IC50 of 68 nM, shows no significant activity against pancreatic lipase or lipoprotein lipase.
Lalistat 1 interferes with neutral lipolysis.
Lalistat 1 binds to active center of neutral lipid hydrolases.

物理化学性质&存储条件

分子量	298.36
分子式	C12H18N4O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-yl morpholine-4-carboxylate

参考文献

1. Bradić I, et al. Mol Metab. 2022 Jul;61:101510.

2. Hamilton J, et al. Clin Chim Acta. 2012 Aug 16;413(15-16):1207-10.