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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Phospholipase-LY311727
LY311727

Chemical Structure : LY311727

CAS No.: 164083-84-5

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LY311727 (LY-311727)

货号: PC-26699Not For Human Use, Lab Use Only.

LY311727 (LY-311727) is a potent and selective inhibitor of human non-pancreatic secretory phospholipase A2 (group IIA sPLA2, PLA2-IIA, hnps-PLA2) with IC50 of 0.19 nM, 1,500-fold selectivity against porcine pancreatic s-PLA2.

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5 mg ￥780 In stock
10 mg ￥1180 In stock
25 mg ￥1980 In stock
50 mg Get quote
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

LY311727 (LY-311727) is a potent and selective inhibitor of human non-pancreatic secretory phospholipase A2 (group IIA sPLA2, PLA2-IIA, hnps-PLA2) with IC50 of 0.19 nM, 1,500-fold selectivity against porcine pancreatic s-PLA2.

物理化学性质&存储条件

分子量 430.44
分子式 C22H27N2O5P
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(3-((3-(2-Amino-2-oxoethyl)-1-benzyl-2-ethyl-1H-indol-5-yl)oxy)propyl)phosphonic acid

参考文献

1. Schevitz RW, et al. Nat Struct Biol. 1995 Jun;2(6):458-65.

2. Fleisch JH, et al. J Pharmacol Exp Ther. 1996 Jul;278(1):252-7.

3. Fox N, et al. Eur J Pharmacol. 1996 Jul 18;308(2):195-203.

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