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首页-小分子抑制剂&激动剂-GPCR-5-HT Receptor-LY272015
LY272015

Chemical Structure : LY272015

CAS No.: 172895-15-7

LY272015 (LY-272015 hydrochloride)

货号: PC-24892Not For Human Use, Lab Use Only.

LY272015 hydrochloride is a potent, selective and orally bioactive 5-HT2B receptor (5-HT2BR) antagonist with IC50 of 0.26 nM.

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5 mg ¥1280 In stock
10 mg ¥1980 In stock
25 mg ¥3580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

LY272015 hydrochloride is a potent, selective and orally bioactive 5-HT2B receptor (5-HT2BR) antagonist with IC50 of 0.26 nM.

物理化学性质&存储条件

分子量 372.89
分子式 C21H25ClN2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(3,4-dimethoxybenzyl)-6-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole hydrochloride

参考文献

1. Watts SW, et al. Am J Physiol. 1999 Mar;276(3):H944-52.

2. Russell A, et al. J Pharmacol Exp Ther. 2002 Oct;303(1):179-87.

3. Santiago Raj PV, et al. ACS Pharmacol Transl Sci. 2025 May 30;8(6):1741-1755.

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