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LRRK2 G2019S inhibitor 17

Chemical Structure : LRRK2 G2019S inhibitor 17

CAS No.:

LRRK2 G2019S inhibitor 17

货号: PC-27142Not For Human Use, Lab Use Only.

LRRK2 G2019S inhibitor 17 is a potent, selective dual inhibitor of LRRK2 G2019S and JNK3 with IC50 of 3.9 and 22.1 nM.

规格 价格 库存 数量
25 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

LRRK2 G2019S inhibitor 17 is a potent, selective dual inhibitor of LRRK2 G2019S and JNK3 with IC50 of 3.9 and 22.1 nM.

物理化学性质&存储条件

分子量 426.91
分子式 C21H23ClN6O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

O=C(N(C)CCCCNC1=NC2=NC3=C1C(Cl)=CN3)C4=CC(N2)=C(OC5CC5)C=C4

参考文献

1. Kim K, et al. J Med Chem. 2026 Jun 22. doi: 10.1021/acs.jmedchem.6c01439.

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