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首页-小分子抑制剂&激动剂-GPCR-Sigma Receptor-LMH-2
LMH-2

Chemical Structure : LMH-2

CAS No.: 132442-35-4

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LMH-2

货号: PC-27163Not For Human Use, Lab Use Only.

LMH-2 is a potent, selective sigma-1 receptor (σ1 R) antagonist with Ki of 6.0 nM, shows high σ1R/σ2R selectivity ratio, displays antihyperalgesic and antiallodynic effects.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

LMH-2 is a potent, selective sigma-1 receptor (σ1 R) antagonist with Ki of 6.0 nM, shows high σ1R/σ2R selectivity ratio, displays antihyperalgesic and antiallodynic effects.

物理化学性质&存储条件

分子量 312.39
分子式 C19H21FN2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(1-benzylpiperidin-4-yl)-4-fluorobenzamide

参考文献

1. Ventura-Martínez R, et al. Biomed Pharmacother. 2024 May;174:116524.

2. Déciga-Campos M, et al. Life Sci. 2020 Mar 15;245:117348.

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