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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Haspin Kinase-LJ5242
LJ5242

Chemical Structure : LJ5242

CAS No.: 2878446-00-3

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LJ5242

货号: PC-24592Not For Human Use, Lab Use Only.

LJ5157 is a LJ4827 derivative and potent, selective inhibitor of mitotic kinase HASPIN with IC50 of 8.27 uM, exhibits strong anti-tumor effects in gemcitabine resistant pancreatic cancer cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

LJ5157 is a LJ4827 derivative and potent, selective inhibitor of mitotic kinase HASPIN with IC50 of 8.27 uM, exhibits strong anti-tumor effects in gemcitabine resistant pancreatic cancer cells.

物理化学性质&存储条件

分子量 332.34
分子式 C12H12N8O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-amino-7-((2R,3R,4S,5R)-5-(azidomethyl)-3,4-dihydroxytetrahydrothiophen-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile

参考文献

1. Shin YZ, et al. Biomed Pharmacother. 2025 May 15;188:118135.

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