LCKLSL | ANXA2 inhibitor | Probechem Biochemicals

Chemical Structure : LCKLSL

CAS No.: 533902-29-3

加入收藏

LCKLSL (Leu-Cys-Lys-Leu-Ser-Leu)

货号: PC-24942Not For Human Use, Lab Use Only.

LCKLSL (Leu-Cys-Lys-Leu-Ser-Leu) is a potent, specific hexapeptide competitive inhibitor of Annexin A2 (AnxA2), inhibits tissue plasminogen activator (tPA)-binding capacity with IC50 of 11 uM.

规格	价格	库存
5 mg	￥1880	In stock
10 mg	￥2980	In stock
25 mg	￥4980	In stock
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

LCKLSL (Leu-Cys-Lys-Leu-Ser-Leu) is a potent, specific hexapeptide competitive inhibitor of Annexin A2 (AnxA2), inhibits tissue plasminogen activator (tPA)-binding capacity with IC50 of 11 uM.
LCKLSL targets the N-terminal tPA-binding site of AnxA2, binds efficiently to cell-surface AnxA2 compared with binding of the control peptide LGKLSL.
LCKLSL inhibits the generation of plasmin and suppresses the VEGF-induced activity of tPA under hypoxic conditions.
LCKLSL prevents hypoxia-induced angiogenic events in in vivo models of angiogenesis.

物理化学性质&存储条件

分子量	675.89
分子式	C30H57N7O8S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	AA sequence: Leu-Cys-Lys-Leu-Ser-Leu

参考文献

1. Hajjar KA, et al. J Biol Chem. 1998 Apr 17;273(16):9987-93.

2. Valapala M, et al. J Cell Sci. 2011 May 1;124(Pt 9):1453-64.

LCKLSL (Leu-Cys-Lys-Leu-Ser-Leu)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

LCKLSL (Leu-Cys-Lys-Leu-Ser-Leu)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.