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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Sodium-coupled Citrate Transporter (NaCT,SLC13A5)-LBA-3
LBA-3

Chemical Structure : LBA-3

CAS No.: 2918263-09-7

LBA-3

货号: PC-26529Not For Human Use, Lab Use Only.

LBA-3 is a highly potent, selective sodium-coupled citrate transporter (NaCT, SLC13A5) with IC50 of 67 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

LBA-3 is a highly potent, selective sodium-coupled citrate transporter (NaCT, SLC13A5) with IC50 of 67 nM.
LBA-3 effectively reduced triglyceride levels in OPA-induced HepG2 cells.
LBA-3 effectively lowered triglyceride and total cholesterol levels in diverse mouse models (PCN-stimulated and starvation-induced), without detectable toxicity.

物理化学性质&存储条件

分子量 314.34
分子式 C18H18O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Butanedioic acid, 2-(2-[1,1'-biphenyl]-4-ylethyl)-2-hydroxy-

参考文献

1. Li'ao Zhang, et al. J Med Chem. 2024 Apr 25;67(8):6687-6704.

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