LB-102 | D(2/3)/5-HT7 inhibitor inhibitor | Probechem Biochemicals

Chemical Structure : LB-102

CAS No.: 2227154-23-4

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LB-102 (LB102)

货号: PC-23209Not For Human Use, Lab Use Only.

LB-102 is an N-methylated analogue of amisulpride, selective dopamine D(2/3)/5-HT(7) inhibitor, binds to the D2 receptor and 5-HT7 receptor with Ki of 0.85 nM and 31 nM respectively, shows potential for treatment of schizophrenia and other psychiatric disorders.

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5 mg	￥1280	In stock
10 mg	￥1980	In stock
25 mg	￥3480	In stock
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生物&药学活性

LB-102 is an N-methylated analogue of amisulpride, selective dopamine D(2/3)/5-HT(7) inhibitor, binds to the D2 receptor and 5-HT7 receptor with Ki of 0.85 nM and 31 nM respectively, shows potential for treatment of schizophrenia and other psychiatric disorders.

物理化学性质&存储条件

分子量	383.51
分子式	C18H29N3O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((1-ethylpyrrolidin-2-yl)methyl)-5-(ethylsulfonyl)-2-methoxy-4-(methylamino)benzamide

参考文献

1. Biernat L, et al. Psychopharmacology (Berl). 2022 Sep;239(9):3009-3018.

2. Grattan V, et al. ACS Omega. 2019 Aug 15;4(9):14151-14154.

LB-102 (LB102)

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LB-102 (LB102)

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