L-869298 (L-869,298)

Chemical Structure : L-869298

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货号: PC-28125Not For Human Use, Lab Use Only.

L-869298 (L-869,298) is a potent, selective and orally active PDE4 inhibitor with IC50 of 0.5 nM for PDE4A, shows less active against hERG.

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L-869298 (L-869,298) is a potent, selective and orally active PDE4 inhibitor with IC50 of 0.5 nM for PDE4A, shows less active against hERG.

分子量	570.45
分子式	C23H18F8N2O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-3-(2-(3-cyclopropoxy-4-(difluoromethoxy)phenyl)-2-(2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)thiazol-5-yl)ethyl)pyridine 1-oxide

1. Friesen RW, et al. J Med Chem. 2003 Jun 5;46(12):2413-26.