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首页-小分子抑制剂&激动剂-GPCR-Dopamine Receptor-L-741626
L-741626

Chemical Structure : L-741626

CAS No.: 81226-60-0

L-741626 (L741626, L-741,626)

货号: PC-28315Not For Human Use, Lab Use Only.

L-741626 is a potent, selective dopamine D2 receptor (D2R, DRD2) antagonist with Ki of 2.4 nM, shows 45-80 fold selectivity over D3 and D4 receptors.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

L-741626 is a potent, selective dopamine D2 receptor (D2R, DRD2) antagonist with Ki of 2.4 nM, shows 45-80 fold selectivity over D3 and D4 receptors.

物理化学性质&存储条件

分子量 340.85
分子式 C20H21ClN2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(4-Chlorophenyl)-1-(1H-indol-3-ylmethyl)-4-piperidinol

参考文献

1. Bowery BJ, et al. Br J Pharmacol. 1996 Dec;119(7):1491-7.

2. Canales JJ, et al. Pharmacol Biochem Behav. 2000 Sep;67(1):161-8.

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